Mouse IL-2 R beta / CD122 Protein, Fc Tag
Mouse IL-2 R beta, Fc Tag (ILB-M5253) is expressed from human 293 cells (HEK293) . It contains AA Ala 27 - Glu 240 (Accession # P16297-1) .
Product Specifications
Background
Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.5 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P16297-1
Expression Region
Ala 27 - Glu 240
Host
HEK293
Target
IL-2 R beta
Conjugation
Unconjugated
Tag
C-Fc
Source
Mouse
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
51.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/ILB-M5253.pdf
Species
Mouse
Curated Selection
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