Cynomolgus / Rhesus macaque Klotho beta Protein, His Tag
KLB (Klotho Beta) is a Protein Coding gene. Among its related pathways are RET signaling and HIV Life Cycle. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL. Klotho Beta is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased expression of βKlotho compared with normal hepatocyte cells. Reintroduction of βKlotho into hepatoma cells inhibited their proliferation.
Product Specifications
Background
Specifications
Accession Number
G7MSR8-1
Expression Region
Phe 53 - Leu 997
Host
HEK293
Target
Klotho beta
Conjugation
Unconjugated
Tag
C-10xHis
Source
Rhesus macaque
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
110.3 kDa
Additionnal Information
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Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Cynomolgus / Rhesus macaque
Protein ID
G7MSR8-1
Preservative
Trehalose
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