Human CLEC4C / BDCA2 Protein, His Tag
CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal (beta1-3/4) GlcNAc (beta1-2) Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Product Specifications
Background
Specifications
Accession Number
Q8WTT0-1
Expression Region
Asn 45 - Ile 213
Host
HEK293
Target
CLEC4C
Conjugation
Unconjugated
Tag
N-10xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human CLEC4C, His Tag (Cat. No. CLC-H5245) at 1 μg/mL (100 μL/well) can bind Litifilimab with a linear range of 0.06-2 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
26.6 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q8WTT0-1
Preservative
Trehalose
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Serratia proteamaculans Molybdenum cofactor biosynthesis protein C (moaC)
Recombinant Serratia proteamaculans Molybdenum cofactor biosynthesis protein C (moaC)
Recombinant Serratia proteamaculans Molybdenum cofactor biosynthesis protein C (moaC)