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Neutral protease I

Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin[1].

Product Specifications

CAS Number

42613-33-2

Product Name Alternative

Dispase I

UNSPSC

12352204

Target

Collagen

Type

Enzyme

Related Pathways

Cytoskeleton

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/neutral-protease-i.html

Smiles

[NeutralproteaseI]

References & Citations

[1]K S Stenn, et al. Dispase, a neutral protease from Bacillus polymyxa, is a powerful fibronectinase and type IV collagenase. J Invest Dermatol. 1989 Aug;93 (2) :287-90.

Shipping Conditions

Room Temperature

Storage Conditions

Store at 4°C for 2 years

Scientific Category

Enzyme

Clinical Information

No Development Reported

Frequently Asked Questions

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