Human GAS6 (279-678) Protein, His Tag (MALS verified)

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 46.0 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q14393-2

Expression Region

Asp 279 - Ala 678

Host

HEK293

Target

GAS6

Conjugation

Unconjugated

Tag

N-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Human GAS6, His Tag (Cat. No. GA6-H5249) at 5 μg/mL (100 μL/well) can bind Human Axl, Fc Tag (Cat. No. AXL-H5253) with a linear range of 0.1-10 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

46.0 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

Q14393-2

Preservative

Trehalose

More Discoveries

Explore Other Products

Browse additional items from our catalog

RC224166A1V 250 µL

Human NKAIN3 (NM_173688) AAV Particle

View Details

040133-APC 200 µL

PLB, phosphorylated (T17) (PLN, PLB, Cardiac phospholamban) (APC) discontinued

View Details

NBP2-99088FR 0.1 mL

Rabbit Polyclonal Cathepsin G Antibody [DyLight 680]

View Details

126012-PE 100 µL

DR3 (Death Receptor 3, DR-3, Apo-3, Apoptosis-inducing Receptor AIR, TRAMP, Death Domain Receptor 3, DDR3, Death Receptor beta, Lymphocyte Associated Receptor of Death, LARD, TR3, Translocating Chain Association Membrane Protein, Tumor Necrosis Factor Receptor Superfamily Member 12, TNFRSF12, Tumor Necrosis Factor Receptor Superfamily Member 25, TNFRSF25, WSL 1, WSL1, WSL-1 Protein, WSL, WSL LR, WSL-LR) (PE)

View Details

C9097-24R 50 µg

Cytokeratin 19 (Cytokeratin-19, CK 19, CK19, CK-19, K1cs, Keratin 19, Keratin-19, K19, Keratin Type I 40kD, Keratin Type I Cytoskeletal 19, KRT19, MGC15366) discontinued, see C9097-24C

View Details

GTR15402633 1 Vial

Human RNF149 Knockout HEK293T cell line

View Details