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Canine LAG-3 / CD223 Protein, His Tag (MALS verified)

Canine LAG-3, His Tag (LA3-C52H7) is expressed from human 293 cells (HEK293) . It contains AA Pro 23 - Leu 440 (Accession # XP_038295087.1) .

Product Specifications

Background

Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.8 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

XP_038295087.1

Expression Region

Pro 23 - Leu 440

Host

HEK293

Target

LAG-3

Conjugation

Unconjugated

Tag

C-10xHis

Source

Canine

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

46.8 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/LA3-C52H7.pdf

Species

Canine

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