Human Nucleolin / NCL Protein, Mouse IgG2a Fc Tag
Human Nucleolin, Mouse IgG2a Fc Tag (NUL-H5254) is expressed from human 293 cells (HEK293) . It contains AA Val 2 - Glu 710 (Accession # P19338-1) .
Product Specifications
Background
Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
Specifications
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 103.5 kDa. The protein migrates as 130-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P19338-1
Expression Region
Val 2 - Glu 710
Host
HEK293
Target
Nucleolin
Conjugation
Unconjugated
Tag
C-mFc (mIgG2a)
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
0.1 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
103.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/NUL-H5254.pdf
Species
Human
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