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Human FGF19 Protein, His Tag

Human FGF19, His Tag (FG9-H51H3) is expressed from E. coli cells. It contains AA Leu 25 - Lys 216 (Accession # O95750-1) .

Product Specifications

Background

Fibroblast growth factor (FGF) 19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF–FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.4 kDa. The protein migrates as 28 kDa under reducing (R) condition (SDS-PAGE) .

Accession Number

O95750-1

Expression Region

Leu 25 - Lys 216

Host

E. coli

Target

FGF19

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, 0.3 M NaCl, 0.3 M Arginine, pH7.4

Additives

Trehalose

Molecular Weight

23.4 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/FG9-H51H3.pdf

Species

Human

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