FXIIa-IN-4
Product Specifications
UNSPSC Description
FXIIa-IN-4 (compound 22) is a potent, selective human FXIIa inhibitor with the IC50 of 0.032 μM, 0.30 μM, ＞50 μM for FXIIa, thrombin and FXIa, respectively. FXIIa-IN-4 can be used for study of anticoagulant[1].
Target Antigen
Factor Xa; Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fxiia-in-4.html
Solubility
DMSO : 26.92 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=NN(C(C2=CC=C(F)C=C2)=O)C(N)=N1)OC
Molecular Weight
264.21
References & Citations
[1]Ma’Lik D. Woodland, et al. New Triazole-Based Potent Inhibitors of Human Factor XIIa as Anticoagulants. ACS Omega 2024, 9, 9, 10694–10708.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163348/FXIIa-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163348/FXIIa-IN-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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