Cynomolgus GPA33 / A33 Protein, His Tag (MALS verified)

Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.6 kDa. The protein migrates as 35-38 kDa and 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

G7NU40-1

Expression Region

Ile 22 - Val 235

Host

HEK293

Target

GPA33

Conjugation

Unconjugated

Tag

C-10xHis

Source

Cynomolgus

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Cynomolgus GPA33, His Tag (Cat. No. GP3-C52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human GPA33 Antibody, Human IgG1 with a linear range of 0.2-2 ng/mL (QC tested).