Human TACI / TNFRSF13B Protein, His Tag
Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) . It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML) . TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA) and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK) 1/2 activation in A549 cells.
Product Specifications
Background
Specifications
Accession Number
O14836-1
Expression Region
Ser 2 - Thr 166
Host
HEK293
Target
TACI
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
Endotoxin
0.1 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
PBS, 0.2 M Arginine, pH7.4
Additives
Trehalose
Molecular Weight
20.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
O14836-1
Preservative
Trehalose
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