Human LIV-1 / SLC39A6 Protein, Fc Tag, low endotoxin
Human LIV-1, Fc Tag (LV1-H5255) is expressed from human 293 cells (HEK293) . It contains AA Phe 29 - Trp 325 (Accession # Q13433-1) .
Product Specifications
Background
LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q13433-1
Expression Region
Phe 29 - Trp 325
Host
HEK293
Target
LIV-1
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
0.05 EU per μg
Purity
95%
Bioactivity
Immobilized Human LIV-1, Fc Tag (Cat. No. LV1-H5255) at 1 μg/mL (100 μL/well) can bind Anti-LIV-1 Antibody, Human IgG1 with a linear range of 0.6-5 ng/mL (QC tested).
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
60.1 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/LV1-H5255.pdf
Species
Human
Curated Selection
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