Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag
Human Mucin-1 (116-173), Fc Tag (MU1-H5256) is expressed from human 293 cells (HEK293) . It contains AA Ser 116 - Gly 173 (Accession # P15941-8) .
Product Specifications
Background
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.7 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P15941-8
Expression Region
Ser 116 - Gly 173
Host
HEK293
Target
Mucin-1
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
32.7 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/MU1-H5256.pdf
Species
Human
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