Human Kremen-1 protein, Fc Tag
Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/β-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6) . Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD) .
Product Specifications
Background
Specifications
Accession Number
Q96MU8-1
Expression Region
Arg 21 - Thr 392
Host
HEK293
Target
KREMEN1
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
67.4 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q96MU8-1
Preservative
Trehalose
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