Human IL-2 R beta&IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)
Selected Variant
ILG-H5254-100ug
Size: 100 µg
Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit) . The high and intermediate affinity forms also associate with a gamma subunit.
Product Specifications
Background
Specifications
Accession Number
P14784-1 (IL-2RB) & P31785-1 (IL-2RG)
Expression Region
Ala 27 - Asp 239 (IL-2RB) & Leu 23 - Asn 254 (IL-2RG)
Host
HEK293
Target
IL-2 R beta & IL-2 R gamma
Conjugation
Unconjugated
Tag
C-Fc | C-Fc
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
51.1 kDa (IL-2RB) and 53.6 kDa (IL-2RG)
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
P14784-1 (IL-2RB) & P31785-1 (IL-2RG)
Preservative
Trehalose
Price
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