Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Mouse IL-3 R alpha / CD123 Protein, His Tag (SPR verified)

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

Product Specifications

Background

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.4 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P26952-1

Expression Region

Ser 17- Lys 331

Host

HEK293

Target

IL-3 R alpha

Conjugation

Unconjugated

Tag

C-10xHis

Source

Mouse

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

36.4 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Mouse

Protein ID

P26952-1

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Spop (NM_001100496) Rat Tagged ORF Clone Lentiviral Particle
RR203648L3V 200 µL

Spop (NM_001100496) Rat Tagged ORF Clone Lentiviral Particle

Ask
View Details
OTOR Antibody
MBS9401406-01 0.1 mL

OTOR Antibody

Ask
View Details
OTOR Antibody
MBS9401406-02 5x 0.1 mL

OTOR Antibody

Ask
View Details
Mouse HTRA4 shRNA Plasmid
abx983631-01 150 µg

Mouse HTRA4 shRNA Plasmid

Ask
View Details
Mouse HTRA4 shRNA Plasmid
abx983631-02 300 µg

Mouse HTRA4 shRNA Plasmid

Ask
View Details
Ampelopsin F
MF-0041957 5 mg

Ampelopsin F

Ask
View Details