Human IL-3 R alpha / CD123 Protein, Llama IgG2b Fc Tag, low endotoxin
Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
Product Specifications
Background
Specifications
Accession Number
P26951-1
Expression Region
Thr 19 - Arg 305
Host
HEK293
Target
IL-3 R alpha
Conjugation
Unconjugated
Tag
C-LlamaFc (LlamaIgG2b)
Source
Human
Stability
Endotoxin
0.01 EU per μg
Purity
90%
Format
Powder
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Additives
Trehalose
Molecular Weight
60.9 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
P26951-1
Preservative
Trehalose
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