Human IL-1RL1 / ST2 Protein, His Tag (MALS verified)

Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.9 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q01638-2

Expression Region

Lys 19 - Phe 328

Host

HEK293

Target

IL-1RL1

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Human IL-1RL1, His Tag (Cat. No. IL1-H5229) at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-33, His,Avitag (Cat. No. IL3-H82H5) with a linear range of 0.02-1.25 μg/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

36.9 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C

Package Size

1mg*1

Host or Source

HEK293

Species

Human

Protein ID

Q01638-2

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS7055386 Inquire

Recombinant Macaca fascicularis Metallophosphoesterase 1 (MPPE1), partial

Ask

View Details

MBS6356580-01 0.2 mL

TMM18, ID (TMEM18, Transmembrane protein 18) (PE)

Ask

View Details

MBS6356580-02 5x 0.2 mL

TMM18, ID (TMEM18, Transmembrane protein 18) (PE)

Ask

View Details

ENZ-CHM223-0010 10 mg

Duvelisib (free base)

Ask

View Details

E43S47336 100 µL

MRPL4 Recombinant Rabbit mAb

Ask

View Details

MBS1089215-01 0.02 mg (E-Coli)

Recombinant Escherichia coli O81 Iron-binding protein IscA (iscA)

Ask

View Details