Human NKG2C / CD159c Protein, His Tag
Human NKG2C, His Tag (NKC-H5248) is expressed from human 293 cells (HEK293) . It contains AA Ile 94 - Leu 231 (Accession # P26717-1 (F102S, mutation caused by sequence update) ) .
Product Specifications
Background
Human NKG2C (NK cell Group 2 isoform C; Killer cell lectin-like receptor subfamily C, member 2) is a member of the C-type lectin-like superfamily of proteins. NKG2C plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The CD94/NKG2C killer lectin-like receptor (KLR) specific for HLA-E is coupled to the KARAP/DAP12 adapter in a subset of NK cells, triggering their effector functions. CD94/NKG2C may operate as an alternative activation pathway for a subset of CD8+ T lymphocytes, triggering their effector functions and proliferation upon specific ligand engagement.
Specifications
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.8 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P26717-1
Expression Region
Ile 94 - Leu 231
Host
HEK293
Target
NKG2C
Conjugation
Unconjugated
Tag
N-10xHis
Source
Human
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
17.8 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
P26717-1
Preservative
Trehalose
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