Mouse IgG1 Fc Protein, Tag Free (MALS verified)
Mouse IgG Fc, Tag Free (IG1-M5208) is expressed from human 293 cells (HEK293) . It contains AA Val 111 - Lys 324 (Accession # AAK53870.1) .
Product Specifications
Background
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport) . IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Specifications
This protein carries no "tag". The protein has a calculated MW of 24.3 kDa. The protein migrates as 28-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
AAK53870.1
Expression Region
Val 111 - Lys 324
Host
HEK293
Target
IgG1 Fc
Conjugation
Unconjugated
Tag
Native
Source
Mouse
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
24.3 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
250ug*4
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/IG1-M5208.pdf
Species
Mouse
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