Human NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified)
CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA) -E on target cells.
Product Specifications
Background
Specifications
Accession Number
P26715-1 (NKG2A) & Q13241-1 (CD94)
Expression Region
Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)
Host
HEK293
Target
NKG2A & CD94
Conjugation
Unconjugated
Tag
C-mFc (mIgG2a)
Source
Human
Stability
Endotoxin
0.1 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
55.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
P26715-1 (NKG2A) & Q13241-1 (CD94)
Preservative
Trehalose
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