Human CD24 Protein, Mouse IgG2a Fc Tag
Human CD24, Mouse IgG2a Fc Tag (CD4-H5257) is expressed from human 293 cells (HEK293) . It contains AA Ser 27 - Gly 59 (Accession # P25063-1) .
Product Specifications
Background
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Specifications
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 30.0 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P25063-1
Expression Region
Ser 27 - Gly 59
Host
HEK293
Target
CD24
Conjugation
Unconjugated
Tag
C-mFc (mIgG2a)
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
0.1 EU per μg
Purity
90%
Bioactivity
Immobilized Human CD24, Mouse IgG2a Fc Tag (Cat. No. CD4-H5257) at 5 μg/mL (100 μL/well) can bind Anti-CD24 MAb (SN3) with a linear range of 20-313 ng/mL (QC tested).
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
30.0 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CD4-H5257.pdf
Species
Human
Curated Selection
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