Biotinylated Human CD52 Protein, His, Avitag™

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs) .ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 13.5 kDa. The protein migrates as 16 kDa and 17-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P31358-1

Expression Region

Gly 25 - Ser 36

Host

HEK293

Target

CD52

Conjugation

Biotin-labeled

Tag

C-10xHis & C-Avi

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Monoclonal Anti-Human CD52 Antibody, Human IgG1 at 10 μg/mL (100 μL/well) can bind Biotinylated Human CD52, His,Avitag (Cat. No. CD2-H82E8) with a linear range of 0.005-0.625 μg/mL (QC tested).