Human ALK-7 Protein, His Tag (MALS verified)
Human ALK-7, His Tag (AL7-H52H5) is expressed from human 293 cells (HEK293) . It contains AA Glu 21 - Glu 113 (Accession # Q8NER5-1) .
Product Specifications
Background
ALK-7 (Activin receptor-like kinase 7) is also known as Activin receptor type-1C, ACTR-IC, ACVR1C. Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.9 kDa. The protein migrates as 15-33 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q8NER5-1
Expression Region
Glu 21 - Glu 113
Host
HEK293
Target
ALK-7
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
20 mM Tris, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
11.9 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/AL7-H52H5.pdf
Species
Human
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