Human Glypican 3 / GPC3 (S495A, S509A) Protein, His Tag (MALS verified)
Human Glypican 3 (S495A, S509A), His Tag (GP3-H52H8) is expressed from human 293 cells (HEK293) . It contains AA Gln 25 - His 559 (Accession # P51654-1 (S495A, S509A) ) .
Product Specifications
Background
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.1 kDa & 24.5 kDa. The protein migrates as 28-32 kDa, 42-45 kDa and 65-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P51654-1 (S495A, S509A)
Expression Region
Gln 25 - His 559
Host
HEK293
Target
Glypican 3
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
0.1 EU per μg
Purity
90%
Bioactivity
Immobilized Human Glypican 3 (S495A, S509A), His Tag (Cat. No. GP3-H52H8) at 0.5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human GPC3 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
38.1 kDa & 24.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/GP3-H52H8.pdf
Species
Human
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS643742-01 0.1 mL
PBX2 (G17, Pre-B-cell Leukemia Transcription Factor 2, Homeobox Protein PBX2, Protein G17)
Ask
View Details 
MBS643742-02 5x 0.1 mL
PBX2 (G17, Pre-B-cell Leukemia Transcription Factor 2, Homeobox Protein PBX2, Protein G17)
Ask
View Details TRC-D479625-100MG 100 mg
1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) (Sodium Salt)
Ask
View Details