Biotinylated Human BTN3A1 / CD277 Protein, Fc, Avitag™

Biotinylated Human BTN3A1, Fc, Avitag (BT1-H82F7) is expressed from human 293 cells (HEK293) . It contains AA Gln 30 - Gly 254 (Accession # O00481-1) .

Product Specifications

Background

Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 52.93 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

O00481-1

Expression Region

Gln 30 - Gly 254

Host

HEK293

Target

BTN3A1

Conjugation

Biotin-labeled

Tag

C-Fc & C-Avi

Source

Human

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.