Alexa Fluor™ 555-Labeled Human Mesothelin / MSLN (296-580) Protein, His TagStar Staining

Alexa Fluor 555-Labeled Human Mesothelin (296-580), His Tag (MSN-HA2H8) is produced via conjugation of AF555 to Human Mesothelin (296-580), His Tag with a new generation site-specific technology under Star Staining labeling platform. Human Mesothelin (296-580), His Tag is expressed from human 293 cells (HEK293) . It contains AA Glu 296 - Gly 580 (Accession # Q13421-3) .

Product Specifications

Background

Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

Specifications

This protein carries a polyhistidine tag at the C-terminus.

Accession Number

Q13421-3

Expression Region

Glu 296 - Gly 580

Host

HEK293

Target

Mesothelin

Conjugation

AF555 Labeled

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.