Human CD48 / SLAMF2 Protein, Mouse IgG2a Fc Tag, low endotoxin

Human CD48 Protein, Mouse IgG2a Fc Tag (BC1-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Ser 220 (Accession # P09326-1).

Product Specifications

Background

CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.

Specifications

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 49.2 kDa. The protein migrates as 64-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Gln 27 - Ser 220

Host

HEK 293

Target

CD48

Conjugation

Unconjugated

Tag

C-mFc(mIgG2a)

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.1 EU per μg

Purity

95%

Bioactivity

Immobilized Human 2B4, Fc Tag (Cat. No. 2B4-H5255) at 2 μg/mL (100 μL/well) can bind Human CD48 Protein, Mouse IgG2a Fc Tag (Cat. No. BC1-H5258) with a linear range of 2-31 ng/mL (QC tested).