Human LILRB3 / CD85a / ILT5 Protein, His Tag (MALS verified)
Human LILRB3, His Tag (CDA-H52H9) is expressed from human 293 cells (HEK293) . It contains AA Gly 24 - Glu 443 (Accession # AAB68668 (P288R) ) .
Product Specifications
Background
Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3, ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48 kDa. The protein migrates as 60-78 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
AAB68668 (P288R)
Expression Region
Gly 24 - Glu 443
Host
HEK293
Target
LILRB3
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
92%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
48 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CDA-H52H9.pdf
Species
Human
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