Human BAFFR / TNFRSF13C Protein, Llama IgG2b Fc Tag, low endotoxin
BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE) . Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
Product Specifications
Background
Specifications
Accession Number
Q96RJ3-1
Expression Region
Ser 7 - Ala 71
Host
HEK293
Target
BAFFR
Conjugation
Unconjugated
Tag
C-LlamaFc (LlamaIgG2b)
Source
Human
Stability
Endotoxin
0.01 EU per μg
Purity
90%
Bioactivity
Format
Powder
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Additives
Trehalose
Molecular Weight
34.4 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q96RJ3-1
Preservative
Trehalose
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