Human CCL17 / TARC Protein, Fc Tag (MALS verified)
Human CCL17, Fc Tag (CC7-H5256) is expressed from human 293 cells (HEK293) . It contains AA Ala 24 - Ser 94 (Accession # Q92583-1) .
Product Specifications
Background
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 34.5 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q92583-1
Expression Region
Ala 24 - Ser 94
Host
HEK293
Target
CCL17
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
50 mM Tris, 100mM Gly, 25mM Arginine, 150mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
34.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
20ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CC7-H5256.pdf
Species
Human
Curated Selection
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