Human CCR8 Full Length Protein (VLP)
Human CCR8 Full Length Protein-VLP (CC8-H52P4) is expressed from human 293 cells (HEK293). It contains AA Asp 2 - Leu 355 (Accession # P51685-1).
Product Specifications
Background
This entry represents CC chemokine receptor 8 (CCR8), which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine). It also exhibits a high affinity for three chemokines of viral origin: vMIP-I, vMIP-II and vMCC-I.
Specifications
This protein .
Expression Region
Asp 2 - Leu 355
Host
HEK 293
Target
CCR8
Conjugation
Unconjugated
Tag
-
Source
Human
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.
Endotoxin
1.0 EU per μg
Bioactivity
Immobilized Human CCR8 Full Length Protein-VLP (Cat. No. CC8-H52P4) at 10 μg/mL (100 μL/well) can bind Anti-CCR8 Antibody, Human IgG1 with a linear range of 0.078-2.5 μg/mL (QC tested).
Format
Liquid
Buffer
PBS, Arginine, pH7.4
Additives
Trehalose
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Documents
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