PE-Labeled Human B7-H3 (4Ig) / B7-H3b Protein, His Tag (Site-specific conjugation)

PE-Labeled Human B7-H3 (4Ig), His Tag (B7B-HP2H9) is produced via site-specific conjugation of PE to Human B7-H3 (4Ig), His Tag under optimal conditions with a proprietary technology. Human B7-H3 (4Ig), His Tag is expressed from human 293 cells (HEK293) . It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1) .

Product Specifications

Background

Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.3 kDa.

Accession Number

Q5ZPR3-1

Expression Region

Gly 27 - Thr 461

Host

HEK293

Target

B7-H3 (4Ig)

Conjugation

PE Labeled

Tag

C-10xHis

Source

Human

Applications

Please note that this product is NOT compatible to streptavidin detection system.

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.