FITC-Labeled Human NCAM-1 / CD56 Protein, His Tag
NCAM1 belongs to the immunoglobulin superfamily of adhesion molecules. A wide range of alternatively spliced NCAM1 messenger RNAs (mRNAs) has been described to date, but only the 120-, 140-, and 180- kDa isoforms are commonly expressed. NCAM1 plays an important role in the regulation of neurogenesis, neurite outgrowth, proliferation, and cell migration, however, its function in hematopoiesis, including NK cells, is poorly understood. NCAM1 signaling is mediated either by homophilic or heterophilic interactions with fibroblast growth factor receptor (FGFR), L1-CAM, N-cadherin and other components of the extracellular matrix. Upon activation, NCAM1 triggers a variety of signaling cascades including FYN–focal adhesion kinase (FAK), MAPK, and phosphatidylinositol 3-kinase (PI3K) pathways.
Product Specifications
Background
Specifications
Accession Number
P13591-2
Expression Region
Leu 20 - Gly 718
Host
HEK293
Target
NCAM-1
Conjugation
FITC Labeled
Tag
C-10xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
50 mM Tris, 500 mM NaCl, pH8.0
Additives
Trehalose
Molecular Weight
79.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C, avoid light
Package Size
25ug*1
Host or Source
HEK293
Species
Human
Protein ID
P13591-2
Preservative
Trehalose
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