Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human Mesothelin / MSLN (296-580) Protein, Fc Tag, premium grade

Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

Product Specifications

Background

Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 58.6 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

AAH09272.1

Expression Region

Glu 296 - Gly 580

Host

HEK293

Target

Mesothelin

Conjugation

Unconjugated

Tag

C-Fc

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.01 EU per μg

Purity

95%

Bioactivity

Immobilized Human Mesothelin (296-580), Fc Tag, premium grade (Cat. No. MSN-H5253) at 0.5 μg/mL (100 μL/well) can bind Anti-Human MSLN Mab with a linear range of 0.1-3 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

58.6 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

AAH09272.1

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Camel Protein Tyrosine Phosphatase Receptor Type N ELISA Kit
MBS089562-01 48 Well

Camel Protein Tyrosine Phosphatase Receptor Type N ELISA Kit

Ask
View Details
Camel Protein Tyrosine Phosphatase Receptor Type N ELISA Kit
MBS089562-02 96 Well

Camel Protein Tyrosine Phosphatase Receptor Type N ELISA Kit

Ask
View Details
Camel Protein Tyrosine Phosphatase Receptor Type N ELISA Kit
MBS089562-03 5x 96 Well

Camel Protein Tyrosine Phosphatase Receptor Type N ELISA Kit

Ask
View Details
Camel Protein Tyrosine Phosphatase Receptor Type N ELISA Kit
MBS089562-04 10x 96 Well

Camel Protein Tyrosine Phosphatase Receptor Type N ELISA Kit

Ask
View Details
Qstatin
MBS3843040-01 5 mg

Qstatin

Ask
View Details
Qstatin
MBS3843040-02 10 mg

Qstatin

Ask
View Details