PE-Labeled Human EGF R Protein, His Tag (Site-specific conjugation)

PE-Labeled Human EGF R, His Tag (EGR-HP2E3) is produced via site-specific conjugation of PE to Human EGF R, His Tag under optimal conditions with a proprietary technology. Human EGF R, His Tag is expressed from human 293 cells (HEK293) . It contains AA Leu 25 - Ser 645 (Accession # P00533-1) .

Product Specifications

Background

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4) . Mutations affecting EGFR expression or activity could result in cancer.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 72.3 kDa.

Accession Number

P00533-1

Expression Region

Leu 25 - Ser 645

Host

HEK293

Target

EGF R

Conjugation

PE Labeled

Tag

C-10xHis

Source

Human

Applications

Evaluation of anti-EGF R CAR expression by flow cytometry. Please note that this product is NOT compatible to streptavidin detection system.

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Format

Powder

Buffer

PBS, 0.5% BSA, pH7.4

Additives

Trehalose

Molecular Weight

72.3 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C, avoid light

Package Size

25tests*1

Host or Source

HEK293

Species

Human

Protein ID

P00533-1

Preservative

Trehalose

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