Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human NKp30 / NCR3 / CD337 Protein, His Tag

Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Product Specifications

Background

Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 13.7 kDa. The protein migrates as 21-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

AAH52582

Expression Region

Leu 19 - Gly 135

Host

HEK293

Target

NKp30

Conjugation

Unconjugated

Tag

C-6xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

13.7 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

500ug*2

Host or Source

HEK293

Species

Human

Protein ID

AAH52582

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

2,4,6-Triiodobenzoic acid
GW0465-500mg 500 mg

2,4,6-Triiodobenzoic acid

Ask
View Details
DCPS Mouse Monoclonal Antibody [Clone ID: LBI4H8]
AMM13325VCF 100 µg

DCPS Mouse Monoclonal Antibody [Clone ID: LBI4H8]

Ask
View Details
RPMI 1640 Medium w/ L-Glutamine, w/o L-Isoleucine, L-Leucine, L-Valine (Liquid)
R8999-20-L 500 mL

RPMI 1640 Medium w/ L-Glutamine, w/o L-Isoleucine, L-Leucine, L-Valine (Liquid)

Ask
View Details
ASB-4 shRNA (m) Lentiviral Particles
sc-141291-V 200 µL

ASB-4 shRNA (m) Lentiviral Particles

Ask
View Details
Recombinant Oryza sativa subsp. japonica Proteasome subunit alpha type-7-B (PAD1)
MBS1356033-01 0.02 mg (E-Coli)

Recombinant Oryza sativa subsp. japonica Proteasome subunit alpha type-7-B (PAD1)

Ask
View Details
Recombinant Oryza sativa subsp. japonica Proteasome subunit alpha type-7-B (PAD1)
MBS1356033-02 0.1 mg (E-Coli)

Recombinant Oryza sativa subsp. japonica Proteasome subunit alpha type-7-B (PAD1)

Ask
View Details