Roquefortine C
Roquefortine C is a mycotoxin that can be isolated from Penicillium species. Roquefortine C is an agonist of P-gp and an inhibitor of P450 3A and P450 1A. Roquefortine C can inhibit Gram-positive bacteria and also has certain neurotoxicity. Additionally, Roquefortine C can exert antitumor activity[1][2][3][4][5].
Product Specifications
CAS Number
58735-64-1
UNSPSC
12352005
Hazard Statement
H301+H311+H331
Target
Bacterial; c-Met/HGFR; Cytochrome P450; P-glycoprotein
Type
Natural Products
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/roquefortine-c.html
Purity
98.42
Solubility
DMSO : 10 mg/mL (ultrasonic; warming)
Smiles
O=C([C@](N1C/2=O)([H])C[C@]3(C(C)(C)C=C)[C@@]1([H])NC4=C3C=CC=C4)NC2=C\C5=CN=CN5
Molecular Formula
C22H23N5O2
Molecular Weight
389.45
Precautions
H301+H311+H331
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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