Human CD4 / LEU3 Protein, His Tag (MALS verified)
T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
Product Specifications
Background
Specifications
Accession Number
P01730
Expression Region
Lys 26 - Trp 390
Host
HEK293
Target
CD4
Conjugation
Unconjugated
Tag
C-6xHis
Source
Human
Stability
Endotoxin
0.1 EU per μg
Purity
90%
Bioactivity
Immobilized Ibalizumab at 1 μg/mL (100 μL/well) can bind Human CD4, His Tag (Cat. No. LE3-H5228) with a linear range of 0.8-6 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
41.51 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*5
Host or Source
HEK293
Species
Human
Protein ID
P01730
Preservative
Trehalose
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