Human BTN1A1 / Butyrophilin Protein, Fc Tag
Human BTN1A1, Fc Tag (BT1-H5253) is expressed from human 293 cells (HEK293) . It contains AA Ala 27 - Arg 242 (Accession # AAH96312) .
Product Specifications
Background
Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Accession Number
AAH96312
Expression Region
Ala 27 - Arg 242
Host
HEK293
Target
BTN1A1
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Additives
Trehalose
Molecular Weight
50.6 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/BT1-H5253.pdf
Species
Human
Curated Selection
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