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Human BTN1A1 / Butyrophilin Protein, Fc Tag

Human BTN1A1, Fc Tag (BT1-H5253) is expressed from human 293 cells (HEK293) . It contains AA Ala 27 - Arg 242 (Accession # AAH96312) .

Product Specifications

Background

Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Accession Number

AAH96312

Expression Region

Ala 27 - Arg 242

Host

HEK293

Target

BTN1A1

Conjugation

Unconjugated

Tag

C-Fc

Source

Human

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

Tris with Glycine, Arginine and NaCl, pH7.5

Additives

Trehalose

Molecular Weight

50.6 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

500ug*2

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/BT1-H5253.pdf

Species

Human

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