Biotinylated Mouse IL-11 R alpha Protein, Avitag™

Receptor for interleukin-11 (IL11) . The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable) . Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.

Product Specifications

Background

Specifications

This protein carries an Avi tag (Avitag™) at the C-terminus. The protein has a calculated MW of 39.8 kDa. The protein migrates as 50 kDa and 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q64385-1

Expression Region

Cys 26 - Gln 367

Host

HEK293

Target

IL-11 R alpha

Conjugation

Biotin-labeled

Tag

C-Avi

Source

Mouse

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

85%

Bioactivity

Immobilized Mouse IL-11 Protein, Fc Tag (Cat. No. IL1-M5243) at 5 μg/mL (100 μL/well) can bind Biotinylated Mouse IL-11 R alpha Protein, Avitag (Cat. No. ILR-M82E8) with a linear range of 0.002-0.625 μg/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

39.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C

Package Size

25ug*1

Host or Source

HEK293

Species

Mouse

Protein ID

Q64385-1

Preservative

Trehalose

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