Human IL-17 RB Protein, Fc Tag
Human IL-17 RB, Fc Tag (ILB-H5251) is expressed from human 293 cells (HEK293) . It contains AA Arg 18 - Pro 292 (Accession # Q9NRM6-1) .
Product Specifications
Background
IL17RB (EVI27, IL17Rh1) is a single pass transmembrane receptor which belongs to IL17R family of cytokine receptors. It was found to be expressed in liver, brain, testis and lungs. The ligand for IL17RB is IL17E, also known as IL25. The five IL-17 receptors (IL17RA-IL17RE) exhibit considerable sequence divergence between one another, but all appear to contain extracellular domains composed of fibronectin type-III (FnIII) domains, and cytoplasmic SEF/IL-17R (SEFIR) domains that show loose homology to Toll/IL-1R (TLR) domains.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.7 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q9NRM6-1
Expression Region
Arg 18 - Pro 292
Host
HEK293
Target
IL-17 RB
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Human IL-17 RB, Fc Tag (Cat. No. ILB-H5251) at 5 μg/mL (100 μL/well) can bind Biotinylated Mouse IL-17E Protein, His,Avitag (Cat. No. ILE-M82E3) with a linear range of 0.06-2 ng/mL (QC tested).
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
56.7 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/ILB-H5251.pdf
Species
Human
Curated Selection
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