Human IL-9 Protein, His Tag (MALS verified)

Interleukin-9 (IL-9) is expressed primarily by activated T cells. The growth factor and anti apoptotic activities of IL-9 on multiple transformed cells suggest a potential role for the cytokine in tumourigenesis. IL-9 has also been proposed as a candidate gene for asthma IL-9 is a Th2-derived cyto kine that has been reported to regulate T and B cell function. IL-9was first isolated as a factor capable of sustaining the long-termgrowth of murine T cell clones, but has since been demon strated to have in vitro activities on mast cells, erythroid pro genitors, and B cell Ig expression.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.0 kDa. The protein migrates as 33-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P15248-1

Expression Region

Gln 19 - Ile 144

Host

HEK293

Target

IL-9

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.1 EU per μg

Purity

90%

Bioactivity

Immobilized Human IL-9 Protein, His Tag (Cat. No. IL9-H52H9) at 5 μg/mL (100 μL/well) can bind Human IL-9R, Fc Tag (Cat. No. ILR-H5251) with a linear range of 5-78 ng/mL (QC tested).