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Mouse MMP-8 Protein, His Tag (active enzyme, MALS verified)

Matrix metalloproteinase-8 (MMP-8) also known as neutrophil collagenase and CLG1, is a member of matrix metalloproteinases (MMPs) family, which degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes as well as pathological processes. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis.

Product Specifications

Background

Matrix metalloproteinase-8 (MMP-8) also known as neutrophil collagenase and CLG1, is a member of matrix metalloproteinases (MMPs) family, which degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes as well as pathological processes. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.9 kDa. The protein migrates as 35-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

O70138-1

Expression Region

Phe 21 - Gly 262

Host

HEK293

Target

MMP-8

Conjugation

Unconjugated

Tag

C-10xHis

Source

Mouse

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Liquid

Buffer

25 mM MES, 150 mM NaCl, 20% Glycerol, pH5.5

Additives

Trehalose

Molecular Weight

28.9 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Host or Source

HEK293

Species

Mouse

Protein ID

O70138-1

Preservative

Trehalose

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