Human IL-18BP Protein, His Tag (MALS & SPR verified)
Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
Product Specifications
Background
Specifications
Accession Number
NP_001138529
Expression Region
Thr 31 - Gly 194
Host
HEK293
Target
IL-18BP
Conjugation
Unconjugated
Tag
C-6xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
18.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
HEK293
Species
Human
Protein ID
NP_001138529
Preservative
Trehalose
Explore Other Products
Browse additional items from our catalog
Transcription Factor E3, Control Peptide (TFE3, Transcription Factor Binding to IGHM Enhancer 3, Transcription Factor for IgH Enhancer) discontinued
Fam188a sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
