Cynomolgus NKp46 / NCR1 / CD335 Protein, Llama IgG2b Fc Tag, low endotoxin
Cynomolgus NKp46, Llama IgG2b Fc Tag (NC1-C5255) is expressed from human 293 cells (HEK293) . It contains AA Pro 22 - Arg 257 (Accession # Q95JB9-1) .
Product Specifications
Background
Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Specifications
This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 54.7 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q95JB9-1
Expression Region
Pro 22 - Arg 257
Host
HEK293
Target
NKp46
Conjugation
Unconjugated
Tag
C-LlamaFc (LlamaIgG2b)
Source
Cynomolgus
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. After reconstitution, this product is stable after storage at -20°C or lower.
Endotoxin
0.01 EU per μg
Purity
90%
Bioactivity
Immobilized Cynomolgus NKp46, Llama IgG2b Fc Tag (Cat. No. NC1-C5255) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-NKp46 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
54.7 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/NC1-C5255.pdf
Species
Cynomolgus
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