PRMT1-IN-2
PRMT1-IN-2 (RM65) is a potent PRMT1 inhibitor with an IC50 of 55.4 μM. PRMT1-IN-2 shows histone hypomethylation in HepG2 cells[1].
Product Specifications
CAS Number
947508-41-0
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt1-in-2.html
Smiles
O=C(C(C)SC1C2=C(OC3=C1C=CC=C3)C=CC=C2)NCCNC(C(C)SC4C5=C(OC6=C4C=CC=C6)C=CC=C5)=O
Molecular Formula
C34H32N2O4S2
Molecular Weight
596.76
References & Citations
[1]Spannhoff A, et al. A novel arginine methyltransferase inhibitor with cellular activity. Bioorg Med Chem Lett. 2007 Aug 1;17 (15) :4150-3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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