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PRMT1-IN-2

PRMT1-IN-2 (RM65) is a potent PRMT1 inhibitor with an IC50 of 55.4 μM. PRMT1-IN-2 shows histone hypomethylation in HepG2 cells[1].

Product Specifications

CAS Number

947508-41-0

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/prmt1-in-2.html

Smiles

O=C(C(C)SC1C2=C(OC3=C1C=CC=C3)C=CC=C2)NCCNC(C(C)SC4C5=C(OC6=C4C=CC=C6)C=CC=C5)=O

Molecular Formula

C34H32N2O4S2

Molecular Weight

596.76

References & Citations

[1]Spannhoff A, et al. A novel arginine methyltransferase inhibitor with cellular activity. Bioorg Med Chem Lett. 2007 Aug 1;17 (15) :4150-3.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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