Human IGFBP-6 Protein, His Tag

IGFBP6 (Insulin-like Growth Factor Binding Protein 6) is a member of the insulin-like growth factor binding protein (IGFBP) family. Like other IGFBPs, IGFBP6 can bind to insulin-like growth factors (IGFs) and modulate their activity and distribution in the body. IGFBP6 is an important regulator of the IGF signaling pathway. It modulates the activity and availability of IGFs, impacting cellular processes and playing a role in development and disease.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.5 kDa. The protein migrates as 30-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P24592

Expression Region

Arg 28 - Gly 240

Host

HEK293

Target

IGFBP-6

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Human IGF-II, Fc Tag (Cat. No. IG2-H4260) at 10 μg/mL (100 μL/well) can bind Human IGFBP-6 Protein, His Tag (Cat. No. IG6-H52H3) with a linear range of 5-156 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

24.5 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C

Package Size

1mg*1

Host or Source

HEK293

Species

Human

Protein ID

P24592

Preservative

Trehalose

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