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Human EBI3 Protein, His Tag

This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27) . IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

Product Specifications

Background

This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27) . IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.3 kDa. The protein migrates as 25-26 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

Accession Number

Q14213

Expression Region

Arg 21 - Lys 229

Host

E. coli

Target

EBI3

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Human IL-27 Protein, Fc Tag, premium grade (Cat. No. IL7-H5254) at 10 μg/mL (100 μL/well) can bind Human EBI3 Protein, His Tag (Cat. No. EB3-H51H3) with a linear range of 0.02-0.625 μg/mL (QC tested).

Format

Powder

Buffer

20 mM NaAc, 150 mM NaCl, pH3.5

Additives

Trehalose

Molecular Weight

25.3 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

E. coli

Species

Human

Protein ID

Q14213

Preservative

Trehalose

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